Научное обоснование
Ознакомьтесь с современным взглядом научного сообщества
Приборы генерируют электромагнитное поле средних частот, естественного безвредного спектра от 1Гц до 990Гц.
Мощность приборов (от 30 до 225Вт) не позволяет обрабатывать большие помещения, однако способно эффективно подавлять большинство известных вирусов, бактерий, грибков и паразитов в радиусе от 1 до 3 метров.
Разработаны международной группой ученых, на основании многолетних научных исследований в области частотно-волнового воздействия на органические патогены:
Германия
- Институт физики им. Макса Планка
- Макс Планк Инновейшн ГмбХ
- Отделение дерматологии, больница Швабинг, Мюнхен
- Кафедра микробиологии, Швабинг, Мюнхен
- Отдел дерматологии, Университетская клиника Регенсбург
- Кафедра невропатологии, TU München
- Институт экспериментальной онкологии, Университет Мюнхена
- Университет ветеринарной медицины, Ганновер
- Кафедра инфекционной и вирусологии, Университет Гейдельберга
- Немецкий аэрокосмический центр (DLR), Кельн
- Немецкий аэрокосмический центр (DLR), Бонн
- Кафедра токсикологии, Университет Мюнхена
- Клиника оториноларингологии (ЛОР), Университет Людвига Максимилиана, Клиника Гросхадерна Мюнхен
- Институт молекулярной патологии, Университет Регенсбург
- Институт биохимии Макса Планка, Мартинсрид
- Клиника анестезиологии, Университет Мюнхена
- Отделение внутренней медицины, Университетская клиника Регенсбург
США
Великобритания
Аппараты сертифицированы в Украине как медицинское физиотерапевтическое оборудование класс 2А
Научное обоснование
Выдержки из публикаций:
«BACTERICIDAL ACTION OF COLD ATMOSPHERIC PLASMA IN SOLUTION»
V Boxhammer1,4, G E Morfill1, J R Jokipii2, T Shimizu1, T Klämpfl1, Y-F Li1, J Köritzer1, J Schlegel3 and J L Zimmermann1
Published 29, New Journal of Physics, Volume 14, November 2012
https://iopscience.iop.org/article/10.1088/1367-2630/14/11/113042
«ХОЛОДНАЯ АТМОСФЕРНАЯ ПЛАЗМА» (cold atmospheric plasma, «САР») является одним из наиболее перспективных инструментов для профилактики инфекционных заболеваний и внутрибольничных инфекций.
Известно, что САР инактивируют широкий спектр микроорганизмов, таких как бактерии, грибы, биопленки, вирусы и споры [ 1 — 6 ]. Очень важным моментом является то, что CAP также способны инактивировать бактерии, устойчивые к антибиотикам, таким как мультирезистентный золотистый стафилококк (MRSA) [ 7 , 8 ].
Даже Deinococcus radiodurans, которые устойчивы к ультрафиолетовому (УФ) излучению, окислению и высыханию, что делает его «самой жесткой бактерией в мире» (как указано в Книге рекордов Гиннеса) могут быть инактивированы в течение нескольких секунд [ 9].
Более того, последние результаты показывают, что микроорганизмы также могут быть инактивированы сквозь различные ткани (текстиль), что открывает еще больше областей применения [10].
Использование CAP в медицине и здравоохранении в качестве дезинфицирующего средства решит многие проблемы — от раздраженной кожи из-за мытья и дезинфекции рук, стерилизации хирургического оборудования до профилактики внутрибольничных инфекций и распространения устойчивых микроорганизмов.
Большое количество исследований, выполненных в последние годы, показали, что все протестированные патогены могут быть легко инактивированы CAP в небольших временных интервалах (от нескольких секунд до минут) [ 1 — 7 , 31 ].»
«PLASMA MEDICINE: AN INTRODUCTORY REVIEW»
M G Kong1, G Kroesen2, G Morfill3,5, T Nosenko3,4, T Shimizu3, J van Dijk2 and J L Zimmermann3,4
Published 26 November 2009 • IOP Publishing and Deutsche Physikalische Gesellschaft
«Устройством для микроволновой плазмы, (разработано под эгидой Института физики им. Макса Планка) обрабатывали мультирезистентный стафилококк аурис (MRSA) плазмой в течение 2 минут, а затем инкубировали в течение 24 часов. Там, где была применена плазма, практически не обнаружено выживших бактерий (определяемых как единичные колониеобразующие единицы), что указывает на снижение бактериальной нагрузки на 99,9999%.
Эти результаты свидетельствуют о том, что САР, безусловно, способны дезактивировать ключевые микробные загрязнители при внутрибольничной инфекции»
Википедия о «PLASMA MEDICINE»
Пресс-релиз Института Плазменной физики им. Макса Планка
Научные источники:
WOUND
Prospective RCT to validate the interval of cold atmospheric plasma treatment for reduction of bacterial load, wound area and pain in patients with chronic wounds,
M. Moelleken, EWMA 2019 (oral presentation)
The Gas Plasma device: a novel therapy in treating non-resolving infected diabetic foot and leg ulcers,
M. Pierides, A. Thant, N. Fleming, M. Gray, P. Grannon, EWMA 2019 conference (e-poster)
Adtec Cold Plasma treatment to assist in treating diabetic foot with multiresistant infection,
A. Thant, M.Gray, P. Grannon, N. Fleming, M. Pierides, ISDF 2019 conference (poster presentation)
Does using a gas plasma medical device change bacterial composition of diabetic foot ulcers and reduce the need for antibiotics?
N. Fleming, P. Grannon, M. Gray, M. Pierides, BSAC Spring Conference 2019 (poster presentation)
Selected Settings of Clinical Plasma Treatment, Urayama et al, Comprehensive Clinical Plasma Medicine,
2018 Springer International Book pages 213-251.
Prospective, randomized and placebo-controlled clinical trial (RCT) for the validation of treatment intervals of chronic wounds with cold atmospheric plasma,
Moelleken, Deutscher Wundkongress 2018 (oral presentation).
Plasma therapy – Once a week enough? Prospective RCT to validate the interval of plasma treatment for reduction of wound area, bacterial load and pain, Jockenhöfer F., EWMA 2018 (oral presentation)
A proof of concept evaluation of the efficacy of non-thermal gas plasma in the treatment of diabetic foot ulcers that are stalled by sub clinical wound infection, McCardle J., Haycocks S., Chadwick P., EWMA 2018 (poster presentation)
Use of cold atmospheric plasma treatment in a chronic burn wound,
Kwang CL, Wounds UK 2015 (poster presentation)
Successful and Safe Use of 2 Min Cold Atmospheric Argon Plasma in Chronic Wounds: Results of A Randomized Controlled Trial.
Isbary, G., J. Heinlin, T. Shimizu, J. L. Zimmermann, G. Morfill, H-U. Schmidt, R. Monetti, B. Steffes, W. Bunk, Y. Li, T. Klaempfl, S. Karrer, M. Landthaler and W. Stolz,. British Journal of Dermatology, 2012. 167(2): p. 404-10.
Cold Atmospheric Plasma (CAP) Changes gene expression of key molecules of the wound healing machinery and improves wound healing in vitro and in vivo.
Arndt S, Unger P, Wacker E, Shimizu T, Heinlin J, Li Y-F, Hubertus T, Morfill GE, Zimmermann JL, Bosserhoff A-K, Karrer S. PLOSONE Nov 2013, Vol 8 Issue 11e79325
Cold atmospheric argon plasma treatment may accelerate wound healing in chronic wounds: Results of a retrospective in vivo randomized controlled study. Isbary G., Stolz W, Shimizu T, Monetti R, Bunk W, Schmidt SteriPlas Bibliography 2019-06-21 V12H-U, Morfill GE, Klaempfl TG, Steffes B, Thomas HM, Heinlin J, Karrer S, Landthaler M, Zimmermann JL Clinical Plasma Medicine 2013 Dec; 1(2):25-30
Randomized placebo-controlled human pilot study of cold atmospheric argon plasma on skin graft donor sites.
Heinlin J, Zimmermann JL, Zeman F, Bunk W, Isbary G, Landthaler M, Maisch T, Monetti R, Morfill, GE, Shimizu T, Steinbauer J, Stolz W, Karrer S. Wound Repair Reg 2013
SURGICAL SITE INFECTION
Cold Atmospheric Plasma and advanced Negative Pressure Wound Treatment: Long term follow up of treated infected implants in cardiac surgery,
H. Rotering, EWMA 2019 (poster presentation)
Infected implant – complex wound treatment: Cold atmospheric plasma and advanced NPWT, H. Rotering, München Chirurgie DGCH 2019 (oral presentation)
Cold atmospheric plasma and advanced negative pressure wound treatment – First results of a tissue saving approach for deep surgical site infections,
H. Rotering, Muenster, S. Martens, Muenster, A. M. Dell’aquila, Muenster EACTS 2018 (Oral presentation)
Cold atmospheric plasma and advanced negative pressure wound treatment – New option for therapy refractory left ventricular assist device infections?
H. Rotering EACTS 2017 (Oral presentation)
Remove it or treat it – New technologies for complicated wounds,
Rotering H., EWMA 2018 (e-poster)
Cold Atmospheric Plasma: Treatment option for critical ill patients with an infected pacemaker pocket,
Rotering H., EWMA 2017, Amsterdam (poster presentation)
Cold Atmospheric Plasma- new options for infection control in wound management,
Rotering H., EWMA 2016, Bremen (oral presentation)
Cold Atmospheric Plasma- new treatment options for infected chronic implants, Rotering H., WUWHS 2016, Florence (oral presentation)
Cold Atmospheric plasma for local infection control and subsequent pain reduction in a patient with chronic post operative ear infection.
Isbary G, Shimizu T, Zimmermann J, Hubertus T, Morfill G, Stolz W. New Microbes and New Infections (2013).
DERMATOLOGY
Efficacy of cold atmospheric plasma versus diclofenac 3% gel in patients with actinic keratoses/field cancerization: preliminary results of a prospective, randomized, rater-blinded study (ACTICAP), K. A. Salva, M. Wirtz, F. Koch, M. McGovern, D. Schadendorf, A. Roesch, EADV 2018 (poster presentation)
Actinic keratoses treated with cold atmospheric plasma,
M. Wirtz, MDI. Stoffels, MD; J. Dissemond, MD; D. Schadendorf, MD; A. Roesch, MD, J. Eur. Acad. Dermatol. Venereol. Online July 11,2017
Randomized placebo-controlled clinical trial showed cold atmospheric argon plasma relieved acute pain and accelerated healing in herpes zoster,
G. Isbary , T. Shimizu, J.L. Zimmermann, J. Heinlin, S. Al-Zaabi, M. Rechfeld, G.E. Morfill, S. Karrer, W. Stolz, Clinical Plasma Medicine, Volume 2, Issue 2, December 2014, Pages 50–55
Cold atmospheric plasma: A successful treatment of lesions in Hailey-Hailey disease, G. Isbary, G. Morfill, J. Zimmermann, T. Shimizu and W. Stolz, Archives of Dermatology 147(4):388-390 (2011)
Plasmamedizin in der Dermatologie,
S Karrer, S Arndt, Der Hautarzt 66(11) · September 2015 SteriPlas Bibliography 2019-06-21 V13
Plasma applications in medicine with a special focus on dermatology,
J. Heinlin, G. Isbary, W. Stolz, G. Morfill, M. Landthaler, T. Shimizu, B. Steffes, T. Nosenko, J. L. Zimmermann and S. Karrer, J. Eur. Acad. Dermatol. Venereol. 25 (1), 1-11 (2011).
Plasma medicine: possible applications in dermatology,
J. Heinlin, G. Morfill, M. Landthaler, W. Stolz, G. Isbary, J. L. Zimmermann, T. Shimizu and S. Karrer, J. Dtsch. Dermatol. Ges. 8 (12), 968-976 (2010).
BIOFILM
The impact of non-thermal gas plasma on bacterial pathogens (planktonic and biofilm phenotype) in-vitro and in an animal model,
K. Cutting TVS UK 2017 (oral presentation)
Antibiofilm Activity demonstrated following treatment with a novel plasma device,
S. Westgate EWMA 2016 Bremen (poster presentation)
The impact of non-thermal gas plasma on bacterial pathogens (planktonic and biofilm phenotype) in-vitro and in an animal model,
K. Cutting EWMA 2016 Bremen (poster presentation))
Antibiofilm Activity demonstrated following treatment with a novel plasma device,
R. Booth, Wounds UK 2015 (poster presentation)
Bactericidal effects of non-thermal argon plasma in vitro, in biofilms and in the animal model of infected wounds,
S. A. Ermolaeva, A. F. Varfolomeev, M. Yu. Chernukha, D. S. Yurov, M. M. Vasiliev, A. A. Kaminskaya, M. M. Moisenovich, J. M. Romanova, A. N. Murashev, I. I. Selezneva, T. Shimizu, E. V. Sysolyatina, I. A. Shaginyan, O. F. Petrov, E. I. Mayevsky, V. E. Fortov, G. E. Morfill, B. S. Naroditsky and A. L. Gintsburg, J. Med.Microbiol. 60, 75-83 (2011).
ANTIMICROBIAL PROPERTIES
The impact of argon gas plasma on bacterial pathogens in vitro and in an animal model,
K. Cutting, EWMA 2018 poster presentation.
Non-thermal gas plasma – mode of action and bioburden management,
Cutting K. Wounds UK, 2016 (poster presentation).
Characterization of Low-Temperature Microwave Plasma Treatment with and without UV Light for Disinfection,
Tetsuji Shimizu, Tetyana Nosenko, Gregor Eugen Morfill, Takehiko Sato, Hans-Ulrich Schmidt and Takuya Urayama, Plasma Process. Polym. 7, 288-293 (2010).
A first prospective randomized controlled trial to decrease bacterial load using cold atmospheric argon plasma on chronic wounds in patients,
G. Isbary, G. E. Morfill, H.-U. Schmidt, M. Georgi, K. Ramrath, J. Heinlin, S. Karrer, M. Landthaler, T. Shimizu, B. Steffes, W. Bunk, R. Monetti, J. L. Zimmermann, R. Pompl and W. Stolz, British J. Dermatol. 163 (1), 78-82 (2010).
Characterization of Microwave Plasma Torch for Decontamination,
Tetsuji Shimizu, Bernd Steffes, René Pompl, Ferdinand Jamitzky, Wolfram Bunk, Katrin Ramrath, Matthias Georgi, Wilhelm Stolz, Hans-Ulrich Schmidt, Takuya Urayama, Shuitsu Fujii, Gregor Eugen Morfill, Plasma Process. Polym. 2008, 5, 577-582
The effect of low-temperature plasma on bacteria as observed by repeated AFM imaging,
René Pompl,Ferdinand Jamitzky, Tetsuji Shimizu, Bernd Steffes, Wolfram Bunk, Hans-Ulrich Schmidt, Matthias Georgi, Katrin Ramrath, Wilhelm Stolz, Robert W. Stark, Takuya Urayama, Shuitsu Fujii and Gregor E. Morfill, New Journal of Physics 11 (2009) 115023 (11pp)
Non-thermal argon plasma is bactericidal for the intracellular bacterial pathogen Chlamydia trachomatis
Svetlana A. Ermolaeva, Elena V. Sysolyatina, Natalia I. Kolkova, Petr Bortsov, Amir I. Tuhvatulin, Mikhail M. Vasiliev,Andrey Y. Mukhachev,Oleg F. Petrov, Shimizu Tetsuji,Boris S. Naroditsky, Gregor E. Morfill, Vladimir E. SteriPlas Bibliography 2019-06-21 V14 Fortov,Anatoly I. Grigoriev, Nelly A. Zigangirova1 and Alexander L. Gintsburg, Journal of Medical Microbiology (2012), 61, 793–799
SAFETY & EFFICACY
Effects and safety of atmospheric low-temperature plasma on bacterial reduction in chronic wounds and wound size reduction: A systematic review and meta-analysis,
O. Assadian, K. J. Ousey, G. Daeschlein et al, Int Wound J. 2018; 1-9.
Comparing two different plasma devices kINPen and Adtec SteriPlas regarding their molecular and cellular effects on wound healing,
Arndt et al, Clinical Plasma Medicine Vol. 9, March 2018 Pages 24-33. MicroPlaSter and SteriPlas, Herbst et al, Comprehensive Clinical Plasma Medicine 2018 Springer International Book pages 503-509.
Cold atmospheric plasma (CAP) activates angiogenesis-related molecules in skin keratinocytes, fibroblasts and endothelial cells and improves wound angiogenesis in an autocrime and paracrine mode,
S. Arndt, P. Unger, M. Berneburg, A. Bosserhoff, Journal of Dermatological Science 89 (2018) 181 – 190.
Investigation of toxicity and mutagenicity of cold atmospheric argon plasma Maisch, T.; Bosserhoff, A. K.; Unger, P.; Heider, J.; Shimizu, T.; Zimmermann, J. L.; Morfill, G. E.; Landthaler, M.; Karrer, S. Environmental and Molecular Mutagenesis, Volume 58, Number 3, 1 April 2017, pp. 172-177(6)
Effects of Cold Atmospheric Plasma (CAP) on ß-Defensins, Inflammatory Cytokines, and Apoptosis-Related Molecules in Keratinocytes In Vitro and In Vivo,
Arndt , S; Landthaler, M. : Zimmemann, J.L; Arndt Unger ,P,: Wacker , E; Shimizu, T: Li, Y-F; Morfill, G.E. dKarrer, S, ‘ PLoS ONE 10(3) · January 2015
A randomized two-sided placebo-controlled study on the efficacy and safety of atmospheric non-thermal argon plasma for pruritus, J. Heinlin, G. Isbary, W. Stolz, F. Zeman, M. Landthaler, G. Morfill, T. Shimizu, J. L. Zimmermann and S. Karrer, J Eur Acad Dermatol Venereol. 27 (3), 324-331 (2013).
Designing plasmas for chronic wound disinfection,
Tetyana Nosenko, Tetsuji Shimizu and Gregor E. Morfill, New Journal of Physics 11 (2009) 115013 (19pp)
LASMA IN MEDICINE
Biological and Microbiological Impact of Plasma Medicine in Wound Healing, Keith Cutting. Wound Healing UK 2016 (oral presentation).
Applications in plasma medicine — a SWOT approach,
Mitra. A., Morfill. G.E., Shimizu. T., Steffes. B., Isbary. G., Schmidt. H.-U., Li. Y.-F., Zimmermann. J.L., Composite Interfaces 19: 231-238, (2012).
Second Special Issue on Plasma Medicine,
M. Laroussi, A. Fridman, P. Favia and M. Wertheimer, Plasma Process. Polym. 7, 193 (2010).
Focus on Plasma Medicine,
Gregor E. Morfill, Michael G. Kong and Julia L. Zimmermann, New Journal of Physics 11 (2009) 115011 (8pp)
Low Temperature Plasmas for Medicine?,
M. Laroussi, IEEE Trans. Plasma Sci., Vol. 37, No. 6, pp. 714-725, 2009
Plasma medicine: an introductory review,
Michael G. Kong, Gerrit Kroesen, Gregor E. Morfill, Tetyana Nosenko, Tetsuji Shimizu, Jan van Dijk and Julia L. Zimmermann, New Journal of Physics 11 (2009) 115012 (35pp)
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German / Deutsch:
- BR online (01-07-2011):
»Bakterien bekämpfen mit Weltraumwind» - Suite 101 (25-06-2011):
»Kill EHEC O104:H4 Vol. 1: Kaltes Plasma macht EHEC-Bakterien kalt» - NZZ (22-06-2011):
»Desinfizieren mit ionisierter Luft» - IDW Online (17-06-2011):
»Kaltes Plasma beseitigt Ehec-Bakterien» - Innovations-Report (17-06-2011):
»Kaltes Plasma beseitigt Ehec-Bakterien» - Klinikdisplay (06-2011):
»Kaltes Plasma beseitigt Ehec-Bakterien» - FAZ (02-2011):
»Grillen wir die Bazillen» - Die Tageszeitung tz (04-2010):
»Plasma-Therapie: Neue Waffe tötet alle Keime» - Médecine & Technique (01-2010): (fr.)
»En finir avec les germes nausocomiaux» - Medizin & Technik (02-2010):
»Keimen keine Chance lassen» - HR-Online.de (10-03-2010):
»Plasma gegen chronische Wunden» - NetDoktor.de (02-03-2010):
»Plasma-Dusche für Bakterien» - Apotheken-Umschau (01-02-2010):
»Plasma gegen Keime» - chemie.de (30-11-2009):
»Neues Gerät tötet resistente Bakterien» - pro-physik.de (29-12-2009):
»Hineinhalten statt Waschen» - n-tv.de (27-11-2009):
»Neues Gerät tötet Bakterien» - Handelsblatt (26-11-2009):
»Neues Gerät tötet resistente Bakterien» - Pressetext Austria (2-02-2010):
»Plasmamedizin: Behandlungsform sorgt für Furore» - Zahnärzte für Niedersachsen (28-12-2009):
»Plasma produzierendes Gerät tötet resistente Bakterien» - Ärztezeitung.de (27-11-2009):
»Neues Gerät tötet resistente Bakterien» - Pharmazeutische Zeitung online (27-11-2009):
»Desinfektion: Mit Weltraumtechnik gegen Bakterien» - Heise Online (1-12-2009):
»Kühles Plasma tötet resistente Keime» - DocCheck News (27-11-2009):
»Mikroblitze gegen resistente Bakterien» - Spektrumdirekt (27-11-2009): (Password required / Passwort benötigt)
»Kühles Plasma tötet resistente Bakterien» - Apotheke Adhoc (27-11-2009):
»Plasma gegen resistente Bakterien» - Welt Online Wissen (27-11-2009):
»Fußpilz durch Socke hindurch den Garaus machen» - Welt der Physik (3-12-2009):
»Desinfizieren und Heilen mit kaltem Plasma» - Kölner Stadt-Anzeiger (27-11-2009):
»Plasmagerät tötet alle Bakterien»
English
- JDDG (08-2010)
»Plasma medicine: possible applications in dermatology» - Journal of the European Academy of Dermatology and Venereology (05-2010)
»Plasma applications in medicine with a special focus on dermatology» - CLEANROOM Technology (27-11-2009)
»PLASMA STERILISATION DEVICE KILLS MRSA» - DNA Read the world (27-11-2009):
»New plasma prototype devices may help destroy MRSA» - FirstScience News (26-11-2009):
»Plasma produces KO cocktail for MRSA» - HospitalHealthCare.com (30-11-2009):
»Eradicating MRSA With New Plasma Technology» - Medical News Today (27-11-2009):
»Eradicating MRSA With New Plasma Technology» - Softpedia (26-11-2009):
»Plasma Prototype Devices Can Destroy MRSA» - EurekAlert (26-11-2009):
»Plasma produces KO cocktail for MRSA» - IOP Institute of Physics (26-11-2009):
»Plasma produces KO cocktail for MRSA»
Cold atmospheric plasma, a new strategy to induce senescence in melanoma cells, S. Arndt, E. Wacker, S. Kaufmann, Y.-F. Li, T. Shimizu, H. M. Thomas, G. E. Morfill, S. Karrer, J. L. Zimmermann and A.-K. Bosserhoff, Experimental Dermatology 22 (4): 284-9 (2013).
Effects of cold atmospheric plasma on mucosal tissue culture, C. Welz, S. Becker, Y.-F. Li, T. Shimizu, J. Jeon, S. Schwenk-Zieger, H. M. Thomas, G. Isbary, G. E. Morfill, U. Harréus and J. L. Zimmermann, Journal of Physics D: Applied Physics 46, 045401 9pp (2013).
Investigation of the mutagenic potential of cold atmospheric plasma at bactericidal dosages, V. Boxhammer, Y-F. Li, J. Köritzer, T. Shimizu, T. Maisch, G. E. Morfill, J. Schlegel and J. L. Zimmermann, Mutation Research in press DOI: 10.1016/j.mrgentox.2012.12.015 (2013).
A randomized two-sided placebo-controlled study on the efficacy and safety of atmospheric non-thermal argon plasma for pruritus, J. Heinlin, G. Isbary, W. Stolz, F. Zeman, M. Landthaler, G. Morfill, T. Shimizu, J. L. Zimmermann and S. Karrer, J Eur Acad Dermatol Venereol. 27 (3), 324-331 (2013).
Ex vivo human skin experiments for the evaluation of safety of new cold atmospheric plasma devices, Isbary. G., Köritzer. J., Mitra. A., Li. Y.-F., Shimizu. T., Schroeder. J., Höpner. I., Klämpfl. T.G., Schlegel. J., Morfill. G.E., Stolz. W., Zimmermann. J.L., Clinical Plasma Medicine, (DOI: http://dx.doi.org/10.1016/j.cpme.2012.10.001), (2013).
Inactivation of surface borne microorganisms and increased germination of seed specimen by Cold Atmospheric Plasma (CAP), Mitra. A., Li. Y.-F. Klämpfl. T.G., Shimizu. T., Jeon. J., Morfill. G.E., Zimmermann. J.L., Food and Bioprocess Technology, (DOI: 10.1007/s11947-013-1126-4) (2013).
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